Research
AAMAC funds research focusing on bone marrow failure diseases such as Aplastic Anemia, PNH and MDS. The following are some of the work we at AAMAC are proud to have funded.
If you have a research project you feel may be of interest and are looking for funding please contact us.
Annual Canadian Nurses Foundation Grant
AAMAC has supported a Canadian Nurses Foundation grant since 2000. The grant is awarded by the Foundation to individuals pursuing graduate nursing studies who specialize in oncology/hematology or who have oncology/hematology as the focus of their research. The Foundation is a national non-profit charitable organization founded in 1962 by the Canadian Nurses Association.
Canadian Aplastic Anemia and Myelodysplastic Syndrome Study (“CAMS”)
AAMAC is supporting the pan-Canadian multicenter registry for aplastic anemia (AA), myelodsyplastic syndromes (MDS), paroxysmal nocturnal hemoglobinuria (PNH) and other acquired bone marrow failure. AAMAC previously provided funding support for the establishment of the Canadian Aplastic Anemia and Myelodysplastic Syndrome Study (see Past Initiatives below).
The CAMS consortium will contribute significantly to enhancing the clinical care of patients with these conditions in the country, and to disseminating knowledge about these rare disorders to the rest of the world.
AAMAC will continue to support the CAMS registry by providing $30,000 CAD per annum for three years, starting on January 1st, 2019 to January 1st, 2022.
Single cell profiling of blood hematopoietic stem cells in pediatric aplastic anemia
AAMAC is supporting a project at B.C. Children’s Hospital.
Healthy lifelong blood production depends on normal functioning stem cells in the bone marrow. Blood stem cells in aplastic anemia (AA), while known to be partially destroyed, are also dysfunctional in their ability to regenerate the blood system. However, the reasons for these underlying deficits remain poorly understood. To advance insights into this area, the study will use the latest sequencing technologies available to profile stem cells in pediatric aplastic anemia at the single cell level to determine if there are distinct biological pathways that explain why AA stem cells fail to restore blood production.
AAMAC will support this research by providing CA$30,000.